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Eflornithine hydrochloride Monohydrate
CAS No. 96020-91-6
Eflornithine hydrochloride Monohydrate ( DFMO | Eflornithine )
产品货号. M16851 CAS No. 96020-91-6
盐酸依氟鸟氨酸水合物（DFMO；MDL-71782）是一种可有效治疗面部多毛症的化合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥243 | 有现货 |
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| 100MG | ￥340 | 有现货 |
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| 200MG | ￥470 | 有现货 |
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| 500MG | ￥1004 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Eflornithine hydrochloride Monohydrate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述盐酸依氟鸟氨酸水合物（DFMO；MDL-71782）是一种可有效治疗面部多毛症的化合物。
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产品描述Eflornithine hydrochloride, hydrate (DFMO; MDL-71782) is a drug found to be effective in the treatment of facial hirsutism.(In Vivo):Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. In subjects with excessive, unwanted facial hair, eflornithine 15% cream is superior to placebo in reducing hair growth. After 24 weeks' treatment, 58% of eflornithine and 34% of placebo subjects have at least some improvement in facial hirsutism. The hair growth inhibitory activity of eflornithine is significantly enhanced when the eflornithine cream is applied onto a mouse skin area pretreated with microneedles. Treatment of coarctation hypertensive rats with eflornithine results in a normalization of the contractile intensity to KCI and norepinephrine and relaxations to acetylcholine by 14 days of hypertension.
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体外实验——
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体内实验Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. In subjects with excessive, unwanted facial hair, eflornithine 15% cream is superior to placebo in reducing hair growth. After 24 weeks' treatment, 58% of eflornithine and 34% of placebo subjects have at least some improvement in facial hirsutism. The hair growth inhibitory activity of eflornithine is significantly enhanced when the eflornithine cream is applied onto a mouse skin area pretreated with microneedles. Treatment of coarctation hypertensive rats with eflornithine results in a normalization of the contractile intensity to KCI and norepinephrine and relaxations to acetylcholine by 14 days of hypertension.
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同义词DFMO | Eflornithine
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通路Others
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靶点Other Targets
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受体Others
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研究领域Other Indications
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适应症——
化学信息
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CAS Number96020-91-6
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分子量236.64
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分子式C6H15ClF2N2O3
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纯度>98% (HPLC)
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溶解度Soluble in DMSO
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SMILESO.Cl.NCCCC(N)(C(F)F)C(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Mohammed A, et al. Y Prev Res (Phila). 2014 Dec;7(12):1198-209.
产品手册
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